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3-O-Methylgallic acid

CAS号

3934-84-7

分子式

C8H8O5

主要靶点

STAT|OCT|Apoptosis|DNA/RNA Synthesis|NF-κB

仅限科研使用

Cat No : CM02086

Print datasheet

Synonyms

Inhibitor|metabolite|RNASynthesis|RNA Synthesis|OCT1|NF-kB|NFkB|NF-κB|NFκB|STAT1|DNASynthesis|DNA Synthesis|inhibit|Anthocyanin|anti-cancer|anti-proliferation|antioxidant|AP-1|Apoptosis|3-O-甲基没食子酸|3OMethylgallic acid|3-O-Methylgallic acid|3 O Methylgallic acid|3,4-Dihydroxy-5-methoxybenzoic acid

验证数据展示

  • CAS No.: 3934-84-7

    3-O-Methylgallic acid
    CAS#: 3934-84-7

产品信息

CAS号 3934-84-7
分子式 C8H8O5
主要靶点 STAT|OCT|Apoptosis|DNA/RNA Synthesis|NF-κB
主要通路 离子通道|细胞周期|DNA 损伤和修复|干细胞|JAK/STAT 信号通路|NF-κB 信号通路|凋亡
分子量 184.15
纯度 98.53%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Inhibitor|metabolite|RNASynthesis|RNA Synthesis|OCT1|NF-kB|NFkB|NF-κB|NFκB|STAT1|DNASynthesis|DNA Synthesis|inhibit|Anthocyanin|anti-cancer|anti-proliferation|antioxidant|AP-1|Apoptosis|3-O-甲基没食子酸|3OMethylgallic acid|3-O-Methylgallic acid|3 O Methylgallic acid|3,4-Dihydroxy-5-methoxybenzoic acid

靶点活性

Cell proliferation:24.1 μM(Caco-2 cells)

体外活性

3,4-Dihydroxy-5-methoxybenzoic acid（10-100 μM）引起细胞活力的时间和剂量依赖性降低[1]。

溶解度

DMSO:37.5 mg/mL (203.64 mM)

参考文献

1.Forester SC, The anthocyanin metabolites gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde decrease human colon cancer cell viability by regulating pro-oncogenic signals. Mol Carcinog. 2014 Jun;53(6):432-9.
2.Gargouri OD, Gargouri B, Trabelsi SK, Bouaziz M, Abdelhédi R. Synthesis of 3-O-methylgallic acid a powerful antioxidant by electrochemical conversion of syringic acid. Biochim Biophys Acta. 2013 Jun;1830(6):3643-9.
3.Forester SC, et al. Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells. J Agric Food Chem. 2010 May 12;58(9):5320-7.

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