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(R)-baclofen

(R)-baclofen (STX209) 是一种选择性GABAB 受体激动剂。

CAS号

69308-37-8

分子式

C10H12ClNO2

主要靶点

GABA Receptor

仅限科研使用

Cat No : CM04194

Print datasheet

Synonyms

Arbaclofen|(R)-巴氯芬|STX209

验证数据展示

  • CAS No.: 69308-37-8

    (R)-baclofen
    CAS#: 69308-37-8

产品信息

(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.

CAS号 69308-37-8
分子式 C10H12ClNO2
主要靶点 GABA Receptor
主要通路 神经科学|离子通道
分子量 213.66
纯度 99.43%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Arbaclofen|(R)-巴氯芬|STX209

体外活性

Baclofen is a skeletal muscle relaxant used in the treatment of spasticity of spinal and cerebral origin. Although it is marketed as a racemic mixture, only the baclofen R-enantiomer is stereospecifically active at so called GAGAB-receptors. [1] Researchers believe that the enantiomers of baclofen have different properties. It is claimed that the R-(?)-enantiomer is about 100 times more active than the S-(+)-enantiomer.

溶解度

H2O:10 mM,DMSO:Insoluble

参考文献

1.Falch E, et al. J Neurochem, 1986, 47(3), 898-903.
2.Penn RD, et al. Lancet, 1984, 1(8385), 1078.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2