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(R)-baclofen

CAS号

69308-37-8

分子式

C10H12ClNO2

主要靶点

GABA Receptor

仅限科研使用

Cat No : CM04194

Print datasheet

Synonyms

Inhibitor|γ-Aminobutyric acid Receptor|STX209|STX-209|STX 209|(R)-巴氯芬|(R)baclofen|(R)-Baclofen|(R) baclofen|Arbaclofen|baclofen|Gamma-aminobutyric acid Receptor|GABA Receptor|GABAReceptor|GABAR|inhibit

验证数据展示

  • CAS No.: 69308-37-8

    (R)-baclofen
    CAS#: 69308-37-8

产品信息

CAS号 69308-37-8
分子式 C10H12ClNO2
主要靶点 GABA Receptor
主要通路 神经科学|离子通道
分子量 213.66
纯度 99.43%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Inhibitor|γ-Aminobutyric acid Receptor|STX209|STX-209|STX 209|(R)-巴氯芬|(R)baclofen|(R)-Baclofen|(R) baclofen|Arbaclofen|baclofen|Gamma-aminobutyric acid Receptor|GABA Receptor|GABAReceptor|GABAR|inhibit

体外活性

Baclofen作为一种骨骼肌松弛剂，用于治疗脊髓和脑源性痉挛。尽管其上市销售形态为外消旋混合物，但只有baclofen R-对映体在所谓的GAGAB受体上具有立体特异性活性。[1] 研究人员相信，baclofen的对映体具有不同的属性。据称，R-()-对映体的活性是S-(+)-对映体的大约100倍。

溶解度

DMSO:Insoluble;H2O:10 mM

参考文献

1.Falch E, et al. J Neurochem, 1986, 47(3), 898-903.
2.Penn RD, et al. Lancet, 1984, 1(8385), 1078.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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=
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C1   V1   C2   V2