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alpha-Cyperone

alpha-Cyperone (α-Cyperone) 与 IL-6, Cox-2, Cdc42, Nck-2, Rac1 的表达下调相关,从而能够抑制炎症反应。

CAS号

473-08-5

分子式

C15H22O

主要靶点

Others|Endogenous Metabolite

仅限科研使用

Cat No : CM03539

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Synonyms

α-香附酮|(+)-α-Cyperone|α-Cyperone

验证数据展示

  • CAS No.: 473-08-5

    alpha-Cyperone
    CAS#: 473-08-5

产品信息

1. Alpha-Cyperone is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. Alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced expression of inducible COX-2 at both the mRNA and the protein levels , downregulated the production and mRNA expression of the inflammatory cytokine IL-6. 3. Alpha-Cyperone inhibited actin cytoskeleton polymerization induced by APEC-O78 through down regulating the expression of Nck-2, Cdc42 and Rac1.

CAS号 473-08-5
分子式 C15H22O
主要靶点 Others|Endogenous Metabolite
主要通路 代谢|其他
分子量 218.34
纯度 98.77%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 α-香附酮|(+)-α-Cyperone|α-Cyperone

溶解度

DMSO:9 mg/mL (41.22 mM)

参考文献

1.Zhang L Y , Lv S , Wu S C , et al. Inhibitory effects of α-cyperone on adherence and invasion of avian pathogenic Escherichia coli O78 to chicken type II pneumocytes[J]. Veterinary Immunology and Immunopathology, 2014, 159(1-2):50-57.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
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C1   V1   C2   V2