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(-)-Anonaine

番荔枝碱

CAS号

1862-41-5

分子式

C17H15NO2

主要靶点

Antioxidant|Antifungal|Apoptosis|Parasite

仅限科研使用

Cat No : CM08094

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Synonyms

番荔枝碱

验证数据展示

  • CAS No.: 1862-41-5

    (-)-Anonaine
    CAS#: 1862-41-5

产品信息

(-)-Anonaine can be extracted from several species of Magnoliaceae and Annelidae and has antimalarial, antibacterial, antifungal, antioxidant, anticancer, antidepressant and vasodilatory activities. (-)-Anonaine induces apoptosis in human cervical cancer (HeLa) cells, induces DNA damage and inhibits the growth and migration of human lung cancer h1299 cells through Bax and caspase-dependent pathways.

CAS号 1862-41-5
分子式 C17H15NO2
主要靶点 Antioxidant|Antifungal|Apoptosis|Parasite
主要通路 微生物学|氧化还原|凋亡
分子量 265.31
纯度 99.22%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 2 years
别名 番荔枝碱

靶点活性

HepG2(cell):38.3 ± 2.3 μg/ml(CC50)|HepG2(cell):23.2 ± 2.7 μg/ml

体外活性

(-)-Anonaine (50-200 μM ; 24h ; ) exhibited significant inhibition to cell growth and migration activities on human lung cancer H1299 cells.[1] (-)-Anonaine (10-200 μM) significant nuclear damages of H1299 cells were observed treatment in a comet assay, whereas higher concentrations (6 and 30 mM) of (-)-anonaine concentrations were required to cause DNA damages in an in vitro plasmid cleavage assay.[1]

溶解度

DMSO:2.65 mg/mL (10 mM)

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2