Recombinant Human MINP1 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human MINP1 protein Ser31-Leu487 (Accession# Q9UNW1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 9562 |
| 蛋白编号 | Q9UNW1 |
| 预测分子量 | 77.7 kDa |
| SDS-PAGE | 70-90 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
MINPP1 (multiple inositol-polyphosphate phosphatase 1), also known as MIPP and MINPP2, is an enzyme that catalyzes the removal of the 3-phosphate group from inositol phosphate substrates. It plays a crucial role in the metabolism of inositol polyphosphates, which are important second messengers in cellular signaling pathways. MINPP1 has been implicated in various diseases, including certain types of cancer, where its expression levels may be associated with tumor progression and differentiation.
参考文献:
1. Ucuncu, Ekin et al. Nature communications vol. 11,1 (2020): 6087. 2. Windhorst, Sabine et al. The Biochemical journal vol. 450,1 (2013): 115-25. 3. Appelhof, Bart et al. European journal of human genetics : EJHG vol. 29,3 (2021): 411-421.
