Recombinant Human NPTN protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human NPTN protein Gln29-Pro339 (Accession# Q9Y639-2) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 27020 |
| 蛋白编号 | Q9Y639-2 |
| 预测分子量 | 60.6 kDa |
| SDS-PAGE | 68-85 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Neuroplastin (Nptn) is a member of the Ig superfamily and is expressed in two isoforms, Np55 and Np65. Np65 contains three Ig domains (Ig1, Ig2, Ig3). Np55 contains only two (Ig2, Ig3). Np65 regulates synaptic transmission, but the function of Np55 is unknown. Expression of the 65 kD neuroplastin (Np65) isoform derived by alternative splicing from the Nptn gene is restricted to brain neurons, whereas the 55 kD isoform (Np55) is present in most cell types but not in glia.
参考文献:
1.Lin, Xiao et al. Brain structure & function vol. 226,5 (2021): 1533-1551. 2.Yagi, Takuya et al. iScience vol. 23,12 101810. 17 Nov. 2020. 3.Suzuki, Jun et al. Proceedings of the National Academy of Sciences of the United States of America vol. 113,34 (2016): 9509-14. 4.Zeng, Wei-Zheng et al. The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 36,35 (2016): 9201-16.
