Recombinant Human Surfactant protein D protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human Surfactant protein D protein Ala21-Phe375 (Accession# P35247) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 6441 |
| 蛋白编号 | P35247 |
| 预测分子量 | 61.5 kDa |
| SDS-PAGE | 65-80 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Surfactant protein-D (SP-D) is a pattern recognition molecule of the collectin family of C-type lectins, which consist of four structural domains: a cysteine-rich N-terminal domain, a collagen-like region, an alpha-helical coiled-coil neck domain and a C-terminal lectin or carbohydrate-recognition domain. SP-D is primarily expressed and secreted by type II alveolar cells. It plays a central role in the pulmonary host defence and the modulation of allergic responses.
参考文献:
1. Kishore U, et al. (2006) Mol Immunol. 43(9):1293-1315. 2. van de Wetering JK, et al. (2004) Eur J Biochem. 271(7):1229-1249. 3. Hartl D, et al. (2006) Eur J Clin Invest. 36(6):423-435.
