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Recombinant Human LGALS3BP protein (rFc Tag) (HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg3302

Print datasheet

Synonyms

90K, BTBD17B, Galectin 3 binding protein, Galectin-3-binding protein, Lectin galactoside-binding soluble 3-binding protein

验证数据展示

  • Purity of Recombinant Human LGALS3BP was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human LGALS3BP was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human LGALS3BP was greater than 90% as determined by SEC-HPLC.

    The purity of Human LGALS3BP was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human LGALS3BP protein Val19-Ser140 (Accession# Q08380) with a rabbit IgG Fc tag at the C-terminus.
基因ID 3959
蛋白编号 Q08380
预测分子量 39.4 kDa
SDS-PAGE 42-55 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-3-binding protein (LGALS3BP, also known as 90K or Mac-2 BP) is a secreted glycoprotein which binds galectin-3, galectin-1, beta1 integrins, collagens and fibronectin. It has been implicated in tumor metastatic processes, as well as in other cell adhesion and immune functions. Levels of LGALS3BP have been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV).

参考文献:

1.  Koths K, et al.J Biol Chem. 268(19):14245-9 (1993).
2. Ullrich A, et al. J Biol Chem. 269(28):18401-7 (1994).
3. Inohara H, et al. Biochem Biophys Res Commun. 201(3):1366-75 (1994).
4. Calabrese G, et al. Cytogenet Cell Genet. 69(3-4):223-5 (1995).
5. Sasaki T, et al. EMBO J. 17(6):1606-13 (1998).
6. Tinari N, et al.  Int J Cancer. 91(2):167-72 (2001).