Recombinant Human NCR3 protein (Myc Tag, His Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
Myc Tag, His Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <1.0 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human NCR3 protein Leu19-Gly135 (Accession# O14931-1) with a Myc tag and a His tag at the C-terminus. |
| 基因ID | 259197 |
| 蛋白编号 | O14931-1 |
| 预测分子量 | 18.4 kDa |
| SDS-PAGE | |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
NKp30 (CD337) (NCR3) is a 30kDa type I transmembrane protein characterized by a single V-type immunoglobulin (Ig) extracellular domain. NKp30 expression is mostly restricted to NK cells , although recent studies found this NCR to be present on the surface of additional immune cells, including γδ T cells and Innate Lymphoid Cells (ILCs). NKp30 is involved in NK cell-mediated killing of various tumor cell lines, virus-infected cells, and also of autologous dendritic cells (DCs) during the so-called "editing" process.
参考文献:
1. Pende, D et al. The Journal of experimental medicine vol. 190,10 (1999): 1505-16. 2. Hudspeth, Kelly et al. Blood vol. 119,17 (2012): 4013-6. 3. Di Vito, Clara et al. Seminars in immunology vol. 41 (2019): 101272.