Recombinant Human MATN3 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human MATN3 protein Asp29-Arg486 (Accession# O15232) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 4148 |
| 蛋白编号 | O15232 |
| 预测分子量 | 75.4 kDa |
| SDS-PAGE | 68-75 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Matrilin-3 (MATN3) is linked to the development of many types of cartilage, and part of the Matrilin family, which includes MATN1, MATN2, MATN3, and MATN4, a family of filamentous-forming adapter oligomeric extracellular proteins that are linked to the formation of cartilage and bone, as well as maintaining homeostasis after development. It is considered an extracellular matrix protein that functions as an adapter protein where the MATN3 subunit can form both homo-tetramers and hetero-oligomers with subunits from MATN1 which is the cartilage matrix protein. This restricted tissue has been strongly expressed in growing skeletal tissue as well as cartilage and bone.
参考文献:
1. Wang, Yi-Chun et al. International journal of molecular medicine vol. 36,6 (2015): 1648-56. 2. Muttigi, Manjunatha S et al. International journal of molecular sciences vol. 17,4 (2016): 590. 3. Pullig, O et al. Osteoarthritis and cartilage vol. 10,4 (2002): 253-63.
