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Recombinant Human Complement C2 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3058

Print datasheet

Synonyms

C2, C3/C5 convertase, CO2, Complement C2, Complement C2a fragment

验证数据展示

  • Purity of Recombinant Human Complement C2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Human Complement C2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human Complement C2 protein Ala21-Leu752 (Accession# P06681-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 717
蛋白编号 P06681-1
预测分子量 107.1 kDa
SDS-PAGE 90-125 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Complement C2 is one of the serum glycoproteins in the classical and MBL pathways of complement activation. C2 is made up of three globular domains. The N-terminal domain, which constitutes the C2b segment, is made up of three short consensus repeats (SCRs). C2 deficiency carries an increased risk of developing systemic lupus erythematosus, recurrent infections and atherosclerosis.

参考文献:

1. Tange CE, et al. (2018). Clin Chem Lab Med. Aug 28;56(9):1498-1506.
2. Huda R, et al. (2013). J Autoimmun. May;42:94-104. 
3. Budding K, , et al. (2021). Neurol Neuroimmunol Neuroinflamm. Nov 10;9(1):e1107. 
4. Laich A, et al. (2022). Immunobiology. May;227(3):152225.