Recombinant Human PIP protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human PIP protein Gln29-Glu146 (Accession# P12273) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 5304 |
| 蛋白编号 | P12273 |
| 预测分子量 | 39.5 kDa |
| SDS-PAGE | 40-48 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
GCDFP-15 (gross cystic disease fluid protein 15), also known as PIP (prolactin-induced protein) is a secretory glycoprotein expressed in benign and malignant breast tumor tissues and in some normal exocrine organs such as sweat, salivary, and lacrimal glands. GCDFP-15 expression is increased by prolactin and androgen and inhibited by estrogen. The expression is also regulated by interleukins. GCDFP-15 is a marker of apocrine differentiation and is frequently used for assessment of metastases or regional recurrences of breast origin.
参考文献:
1. Ciullo, Marina et al. Human molecular genetics vol. 11,23 (2002): 2887-94. 2. Hassan, Md I et al. Cellular and molecular life sciences : CMLS vol. 66,3 (2009): 447-59.
