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Recombinant Human CD62L protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3006

Print datasheet

Synonyms

CD62L, L-selectin, CD62 antigen-like family member L, gp90 MEL, gp90-MEL

验证数据展示

  • Purity of Recombinant Human CD62L was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Human CD62L was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human CD62L protein Trp39-Asn332 (Accession# P14151-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 6402
蛋白编号 P14151-1
预测分子量 59.1 kDa
SDS-PAGE 68-80 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CD62L, also known as L-selectin or SELL, is a member of the selectin family of adhesion molecules that also include CD62E (E-selectin) and CD62P (P-selectin). CD62L is a highly glycosylated protein of 95-105 kDa on neutrophils and 74 kDa on lymphocytes. CD62L is expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes. It mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and is also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation.

参考文献:

1.Bowen BR. et al. (1989) J Cell Biol. 109(1):421-427.
2.Tedder TF. et al. (1989) J Exp Med. 170(1):123-133.
3.Griffin JD. et al. (1990) J Immunol. 145(2):576-584.
4.Tedder TF. et al. (1990) Eur J Immunol. 20(6):1351-1355. 
5.Tedder TF. et al. (1990) J Immunol. 144(2):532-540.
6.Schleiffenbaum B. et al. (1992) J Cell Biol. 119(1):229-238.