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Recombinant Mouse Decorin protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2955

Print datasheet

Synonyms

Bone proteoglycan II, Dcn, Decorin, PG40, PG-S2

验证数据展示

  • Purity of Recombinant Mouse Decorin was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse Decorin was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Mouse Decorin protein Gly17-Lys354 (Accession# P28654) with a rabbit IgG Fc tag at the C-terminus.
基因ID 13179
蛋白编号 P28654
预测分子量 64.0 kDa
SDS-PAGE 68-73 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Decorin is a member of the small leucine-rich proteoglycan family of proteins. Decorin interacts with type I collagen fibrils, thereby influencing the kinetics of fibril formation and the distance between adjacent collagen fibrils. The binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. Decorin(~ 40 kDa) also binds glycosaminoglycan chains to form big molecules.

参考文献:

1. McInturff S, Coen FV, et al. (2022) J Assoc Res Otolaryngol. 23(3):391-412. 
2. Shi Y, Wu X, et al. (2022) Adv Sci (Weinh). 9(7):e2104112. 
3. Lall SP, Alsafwani ZW, et al. (2024) Biochim Biophys Acta Rev Cancer. 1879(1):189029. 
4. Zhang J, Chen H, et al.  (2022) Neurosci Bull. 38(5):459-473.