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Recombinant Mouse NKp46/NCR1 protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg1825

Print datasheet

Synonyms

Ncr1, Activating receptor 1, CD335, Ly94, Lymphocyte antigen 94

验证数据展示

  • Purity of Recombinant Mouse NKp46 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse NKp46 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Mouse NKp46 protein Gln17-Asn255 (Accession# Q8C567) with a rabbit IgG Fc tag at the C-terminus.
基因ID 17086
蛋白编号 Q8C567
预测分子量 53.4 kDa
SDS-PAGE 60-70 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals. NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail. It is expressed on NK cells, rare T-cell subsets and a mucosal population of NKp46+ innate lymphoid cells. NKp46 is the major triggering receptor involved in the natural cytotoxicity.

参考文献:

1.Narni-Mancinelli E, et al. (2011) Proc Natl Acad Sci U S A. 108(45):18324-9.
2.Pessino A, et al. (1998) J Exp Med. 188(5):953-60.
3.Narni-Mancinelli E, et al. (2011) Proc Natl Acad Sci U S A. 108(45):18324-9.
4.Sivori S, et al. (1999) Eur J Immunol. 29(5):1656-66.
5.Biassoni R, et al. (1999) Eur J Immunol. 29(3):1014-20.
6.Westgaard IH, et al. (2004) J Leukoc Biol. 76(6):1200-6.