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Recombinant Human NKp46/NCR1 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg1364

Print datasheet

Synonyms

CD335, hNKp46, LY94, Natural killer cell p46-related protein, NCR 1

验证数据展示

  • Purity of Recombinant Human NKp46 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human NKp46 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human NKp46 protein Gln22-Arg258 (Accession# EAW72309.1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 9437
蛋白编号 EAW72309.1
预测分子量 53.1 kDa
SDS-PAGE 55-70 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals. NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail. It is expressed on NK cells, rare T-cell subsets and a mucosal population of NKp46+ innate lymphoid cells. NKp46 is the major triggering receptor involved in the natural cytotoxicity.

参考文献:

1. Narni-Mancinelli E. et al. (2011). Proc Natl Acad Sci U S A. 108(45):18324-9.
2. Pessino A. et al. (1998). J Exp Med. 188(5):953-60.
3. Sivori S. et al. (1999). Eur J Immunol. 29(5):1656-66.
4. Biassoni R. et al. (1999). Eur J Immunol. 29(3):1014-20.
5. Westgaard IH. et al. (2004). J Leukoc Biol. 76(6):1200-6.