Recombinant Human OX40L/TNFSF4 protein (mFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
mFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human OX40L protein Gln51-Leu183 (Accession# P23510) with a mouse IgG Fc tag at the N-terminus. |
| 基因ID | 7292 |
| 蛋白编号 | P23510 |
| 预测分子量 | 43.1 kDa |
| SDS-PAGE | 45-55 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
OX40L (OX40 Ligand) is a crucial protein in the immune system that plays a pivotal role in activating and regulating T cells. It belongs to the tumor necrosis factor (TNF) superfamily and is also known as TNFSF4, gp34, or CD252. It is primarily expressed on the surface of antigen-presenting cells (APCs), such as activated B cells, dendritic cells, and macrophages. It is also found on non-immune cells like vascular endothelial cells and smooth muscle cells.
参考文献:
1. Sadrolashrafi, Kaviyon et al. Cells vol. 13,7 587. 2024 2. Webb, Gwilym J et al. Clinical reviews in allergy & immunology vol. 50,3 (2016): 312-32. 3. Lé, Ana Maria, and Tiago Torres. Pharmaceutics vol. 14,12 2753. 2022
