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Recombinant Human B7-H6 protein (Myc Tag, His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

Myc Tag, His Tag

生物活性

未测试

Cat no : Eg0007

Print datasheet

Synonyms

B7H6, NCR3LG1, B7 H6, B7 homolog 6, Natural cytotoxicity triggering receptor 3 ligand 1

验证数据展示

  • Purity of Recombinant Human PCSK9 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human PCSK9 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <1.0 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human B7-H6 protein Asn25-Ser262 (Accession# Q68D85) with a Myc tag and a His tag at the C-terminus.
基因ID 374383
蛋白编号 Q68D85
预测分子量 32.3 kDa
SDS-PAGE
组分 Lyophilized from sterile PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

B7-H6, also known as NCR3LG1, is a co-stimulatory ligand that plays a crucial role in the immune response by binding to the natural killer (NK) cell activating receptor NKp30. It was reported that B7-H6 has inhibitory effects on cell proliferation and migration. It is primarily localized in the cell membrane of tumor cells, where it can interact with NKp30 on NK cells. In some cases, B7-H6 can also be found in the intracellular space of cancer cells, such as in small cell lung cancer (SCLC).

参考文献:

1.Mohammadi, Alaleh et al. Life sciences vol. 304, (2022): 120709.
2.Brandt, Cameron S et al. The Journal of experimental medicine vol. 206,7 (2009): 1495-503.
3.Zhang, Xiuqin et al. Annals of translational medicine vol. 8,9 (2020): 589.
Banu, Nehla et al. BMC cancer vol. 20,1 (2020): 1083.