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验证数据展示

  • WB analysis using 87433-1-RR (same clone as 87433-1-PBS)

    WB analysis using 87433-1-RR (same clone as 87433-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 87433-1-RR (CD315/PTGFRN antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87433-1-PBS in a different storage buffer formulation.

  • Cytometric bead array sample test of MP02983-1

    Cytometric bead array sample test of MP02983-1

    The mean PTGFRN concentration was determined to be 62.7 ng/mL in mouse lung tissue extract based on a 5.0 mg/mL extract load, 23.5 ng/mL in mouse spleen tissue extract based on a 6.4 mg/mL extract load, 9.0 ng/mL in NIH/3T3 cell extract based on a 1.2 mg/mL extract load.

  • Cytometric bead array standard curve of MP02983-1

    Cytometric bead array standard curve of MP02983-1

    Cytometric bead array standard curve of MP02983-1, MOUSE PTGFRN Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 87433-2-PBS. Detection antibody: 87433-1-PBS. Standard: Eg6319. Range: 0.781-100 ng/mL.

  • Affinity of 87433-1-RR

    Affinity of 87433-1-RR

    Biolayer interferometry (BLl) kinetic assays of 87433-1-RR against Mouse CD315/PTGFRN were performed. The affinity constant is 54.3 pM.

Mouse CD315/PTGFRN Recombinant monoclonal antibody, PBS Only (Detector)

CD315/PTGFRN Uni-rAb® Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 87433-1-PBS

产品说明书

CloneNo. 252390C10

宿主/亚型

Rabbit / IgG

种属反应性

mouse, rat

应用

WB, Cytometric bead array, Indirect ELISA

别名

CD315, CD9 partner 1, CD9P-1, EWI-F, Fprp

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

87433-1-PBS targets CD315/PTGFRN as part of a matched antibody pair:

MP02983-1: 87433-2-PBS capture and 87433-1-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 mouse, rat
免疫原

CatNo: Eg6319

Product name: Recombinant Mouse PTGFRN/CD315 protein (C-rFc)

Source: mammalian cells-derived, V37

Tag: C-rFc

Domain: 22-832 aa of NM_011197.3

Sequence: RVVRVPAGTLVRVVGTELVIPCNVSDYDGPSEQNFDWSFSSSGSSFVELASTWEVGFPAQLYRERLQRGDILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADALVVGPSSRPPPGLSLREGEPFELRCIASTTSPLHTHLALRWELHRGPVHRSILALSHEGRFHPGPGYEQRYHSGDVRLDTVGSDAYRLSVARALSADQGSYRCVVSEWITEQGSWQEIQEKAVEVATVVIQPTALQLAVPRTVSVTEGKDLDLSCNITTDRVDDVRPEVTWYFKKTPDTSLLASHMLARLDRDSLVHSSPHVALSHVDTRSYHLLVRDVSKENSGYYLCLVALWAPGHNRSWHKVAEAMSAPSGVSVTWLEPEYQVYLNASKVPGFSDDPTELQCRVIDTKRLEAGVRLTVSWYYRMTRRNDDVVASELLAVMDGDWTLRYGERSKQRAQDGEFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTRQRNNSWVKSKDVFSKPVNIFWASEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLITAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPIGGSLWREAATSLSNPIEIDFQTSGPTFNASVHSDTPSVTRGDLIKLFCIVTVEGAVLDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGVVTTGQRDWKSTVSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVRSPTGSWQREAEIHSRPIFITVKMDVLNAFKYP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 prostaglandin F2 receptor negative regulator
别名 CD315, CD9 partner 1, CD9P-1, EWI-F, Fprp
计算分子量99 kDa
观测分子量 100-130 kDa
GenBank蛋白编号NM_011197.3
基因名称 Ptgfrn
Gene ID (NCBI) 19221
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9WV91
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PTGFRN (Prostaglandin F2 Receptor Negative Regulator), also known as CD315, is a trans-membrane protein that modulates prostaglandin F2α signaling and links the tetraspanin web to the cytoskeleton, it is now recognized as a driver of metastasis; high expression correlates with aggressive proliferation, migration, and spheroid growth in epidermoid carcinoma, medulloblastoma, and mesothelioma, while silencing PTGFRN impairs these traits and disrupts autophagy (PMID: 38924562). The calculated value of PTGFRN is 98 kDa. It has multiple glycosylation sites and its molecular weight after glycosylation is approximately 100 - 130 kDa.

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