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验证数据展示

  • WB analysis using 85052-4-RR (same clone as 85052-4-PBS)

    WB analysis using 85052-4-RR (same clone as 85052-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85052-4-RR (TIGAR antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85052-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85052-4-PBS

    Affinity and Kinetic Characterization of 85052-4-PBS

    Biolayer interferometry (BLl) kinetic assays of 85052-4-PBS against Human TIGAR were performed. The affinity constant is 0.306 nM.

  • Affinity and Kinetic Characterization of 85052-4-RR

    Affinity and Kinetic Characterization of 85052-4-RR

    Biolayer interferometry (BLl) kinetic assays of 85052-4-RR against Human TIGAR were performed. The affinity constant is 0.308 nM.

TIGAR Recombinant antibody, PBS Only

TIGAR Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85052-4-PBS

产品说明书

CloneNo. 242625E7

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

C12orf5, 242625E7, EC:3.1.3.46, Fructose-2,6-bisphosphatase TIGAR, TP53-induced glycolysis and apoptosis regulator

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

85052-4-PBS targets TIGAR in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 TIGAR fusion protein Ag17532 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 chromosome 12 open reading frame 5
别名 C12orf5, 242625E7, EC:3.1.3.46, Fructose-2,6-bisphosphatase TIGAR, TP53-induced glycolysis and apoptosis regulator
计算分子量 270 aa, 30 kDa
观测分子量 30 kDa
GenBank蛋白编号BC012340
基因名称 TIGAR
Gene ID (NCBI) 57103
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9NQ88
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The TP53-induced glycolysis and apoptosis regulator (TIGAR), first reported in 2006, is a downstream target gene of p53 and an important factor involved in glycolysis and apoptosis . It is indispensable in metabolism and is involved in metabolic syndrome, including hyperglycemia, insulin resistance, alcoholic fatty liver and tissue ischemia. TIGAR is highly expressed in many cancer cells to promote cell survival.