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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 84659-1-RR (same clone as 84659-1-PBS)

    WB analysis using 84659-1-RR (same clone as 84659-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84659-1-RR (Axl antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84659-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 84659-1-RR (same clone as 84659-1-PBS)

    IF Staining of HeLa using 84659-1-RR (same clone as 84659-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using AXL antibody (84659-1-RR, Clone: 242014B9 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84659-1-PBS in a different storage buffer formulation.

AXL Recombinant antibody, PBS Only

AXL Uni-rAbTM Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 84659-1-PBS

产品说明书

CloneNo. 242014B9

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF/ICC, Indirect ELISA

别名

242014B9, EC:2.7.10.1, Tyrosine-protein kinase receptor UFO, UFO

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

84659-1-PBS targets AXL in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原 AXL fusion protein Eg1618 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 AXL receptor tyrosine kinase
别名 242014B9, EC:2.7.10.1, Tyrosine-protein kinase receptor UFO, UFO
计算分子量98kDa
观测分子量130-140 kDa
GenBank蛋白编号NM_021913.4
基因名称 AXL
Gene ID (NCBI) 558
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP30530-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Axl, also known as Ufo or Ark, is a receptor tyrosine kinase of the TAM (Tyro3, Axl and Mer) family. Axl is a single-pass type I membrane protein containing two fibronectin type-III domains, two Ig-like C2-type domains and one protein kinase domain. Axl mRNA is widely expressed with highest levels in the heart and skeletal muscle. Gas6 has been identified as a ligand for human Axl. Gas6/Axl signaling plays a role in cell survival, cell proliferation, migration and differentiation. It has been reported that 110-120 kDa non-glycosylated AXL protein can be detected(PMID: 31171001). Endogenous Axl is auto-phosphorylated and reacted with a tyrosine-phosphorylated protein of 140 kDa(PMID: 12730092).