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验证数据展示

  • IF Staining of rat brain using 83251-2-RR (same clone as 83251-2-PBS)

    IF Staining of rat brain using 83251-2-RR (same clone as 83251-2-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded rat brain tissue using NRG1, isoform Alpha antibody (83251-2-RR, Clone: 240067A6 ) at dilution of 1:500 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83251-2-PBS in a different storage buffer formulation.

  • IF Staining of MCF-7 using 83251-2-RR (same clone as 83251-2-PBS)

    IF Staining of MCF-7 using 83251-2-RR (same clone as 83251-2-PBS)

    Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using NRG1, isoform Alpha antibody (83251-2-RR, Clone: 240067A6 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83251-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83251-2-PBS

    Affinity and Kinetic Characterization of 83251-2-PBS

    Biolayer interferometry (BLl) kinetic assay of 83251-2-PBS against Human NRG1, isoform Alpha was performed. The affinity constant is 16.9 nM.

NRG1, isoform Alpha Recombinant antibody, PBS Only

NRG1, isoform Alpha Uni-rAbTM Recombinant Antibody for IF/ICC, IF-P, Cytometric bead array, Indirect ELISA
Cat No. 83251-2-PBS

产品说明书

CloneNo. 240067A6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IF/ICC, IF-P, Cytometric bead array, Indirect ELISA

别名

NRG1, NRG1A, 240067A6, ARIA, GGF

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

83251-2-PBS targets NRG1, isoform Alpha in IF/ICC, IF-P, Cytometric bead array, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IF/ICC, IF-P, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 NRG1, isoform Alpha fusion protein Ag35114 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 neuregulin 1
别名 NRG1, NRG1A, 240067A6, ARIA, GGF
计算分子量 70 kDa
观测分子量 70 kDa
GenBank蛋白编号BC007675
基因名称 NRG1
Gene ID (NCBI) 3084
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ02297
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Neuregulin 1 (NRG1) is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by usage of different promoters and alternative splicing of a single gene. NRG1 and its receptor ErbB tyrosine kinase are expressed not only in the developing nervous system, but also in the adult brain. The immunogen of this antibody is against NRG1 isoform Alpha.