验证数据展示
产品信息
83039-1-PBS targets SALL4 in Sandwich ELISA, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | Sandwich ELISA, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | SALL4 fusion protein Ag16076 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | sal-like 4 (Drosophila) |
| 别名 | 230284B7, DRRS, HSAL4, Sal like protein 4, Sal-like protein 4 |
| 计算分子量 | 1053 aa, 112 kDa |
| GenBank蛋白编号 | BC111714 |
| 基因名称 | SALL4 |
| Gene ID (NCBI) | 57167 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9UJQ4 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SALL4, also named Sal-like protein 4 or Zinc finger protein 797, Contains 7 C2H2-type zinc fingers and belongs to the sal C2H2-type zinc-finger protein family. SALL4 is constitutively expressed in acute myeloid leukemia. The constitutive expression of SALL4 in mice is sufficient to induce MDS-like symptoms and transformation to AML that is transplantable. SALL4 is able to bind beta-catenin and activate the Wnt/beta-catenin signaling pathway.