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验证数据展示

  • WB analysis of mouse heart using 55438-1-AP

    WB analysis of mouse heart using 55438-1-AP

    mouse heart tissue were subjected to SDS PAGE followed by western blot with 55438-1-AP (SCN4B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  • IHC staining of human skeletal muscle using 55438-1-AP

    IHC staining of human skeletal muscle using 55438-1-AP

    Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 55438-1-AP (SCN4B Antibody) at dilution of 1:50 (under 10x lens).

  • IHC staining of human skeletal muscle using 55438-1-AP

    IHC staining of human skeletal muscle using 55438-1-AP

    Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 55438-1-AP (SCN4B Antibody) at dilution of 1:50 (under 40x lens).

SCN4B Polyclonal antibody

SCN4B Polyclonal Antibody for WB, IHC, ELISA
Cat No. 55438-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, ELISA

别名

SCN4B, Sodium channel subunit beta 4

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inmouse heart tissue, mouse brain tissue
Positive IHC detected inhuman skeletal muscle tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

55438-1-AP targets SCN4B in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human, mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 sodium channel, voltage-gated, type IV, beta
别名 SCN4B, Sodium channel subunit beta 4
计算分子量 25 kDa
观测分子量 28 kDa
GenBank蛋白编号NM_174934
基因名称 SCN4B
Gene ID (NCBI) 6330
RRIDAB_2881331
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8IWT1
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Aliquoting is unnecessary for -20oC storage.

背景介绍

Mammalian sodium channels are heterotrimers, composed of a central, pore-forming alpha subunit and two auxiliary beta subunits (PMID: 11486343). SCN4B (sodium channel subunit beta-4) is one of several sodium channel beta subunits, which modulate channel gating kinetics. SCN4B has an N-terminal signal peptide, a large extracellular domain predicted to form an Ig-like fold, a single transmembrane alpha helix, and a short cytoplasmic C terminus. Defects in SCN4B gene are a cause of long QT syndrome type 10 (LQT10).

实验方案

Product Specific Protocols
WB protocol for SCN4B antibody 55438-1-APDownload protocol
IHC protocol for SCN4B antibody 55438-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols