CoraLite® Plus 488-conjugated TROVE2 Monoclonal antibody
TROVE2 Monoclonal Antibody for FC (Intra)
Host / Isotype
Mouse / IgG2a
Reactivity
Human, Mouse, Rat
Applications
FC (Intra)
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2A4E5
验证数据展示
经过测试的应用
Positive FC detected in | A549 cells |
For other applications, we recommend the unconjugated version of this antibody, 67149-1-Ig
推荐稀释比
Application | Dilution |
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Flow Cytometry (FC) | FC : 0.40 ug per 10^6 cells in a 100 µl suspension |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-67149 targets TROVE2 in FC (Intra) applications and shows reactivity with Human, Mouse, Rat samples.
Tested Applications | FC (Intra) |
Tested Reactivity | Human, Mouse, Rat |
Immunogen | TROVE2 fusion protein Ag4379 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | TROVE domain family, member 2 |
Synonyms | 60 kDa ribonucleoprotein Ro, 60 kDa Ro protein, Ro 60 kDa autoantigen, RO60, RoRNP, Sjoegren syndrome antigen A2, SS A, SSA2, TROVE domain family member 2, TROVE domain family, member 2, TROVE2 |
Calculated Molecular Weight | 60 kDa |
Observed Molecular Weight | 60 kDa |
GenBank Accession Number | BC036658 |
Gene Symbol | TROVE2 |
Gene ID (NCBI) | 6738 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P10155 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TROVE2, also named as RO60 or RoRNP, is a 538 amino acid protein, which is localized in cytoplasmic mRNP granules containing untranslated mRNAs. TROVE2 as a RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. TROVE2 may stabilize some of these RNAs and protect them from degradation (PubMed:18056422). TROVE2 binds to endogenous Alu retroelements which are induced by type I IFN and stimulate porinflammaotry cytokine secretion.
实验方案
Product Specific Protocols | |
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FC protocol for CL Plus 488 TROVE2 antibody CL488-67149 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |