CoraLite® Plus 488-conjugated PTGS1 Monoclonal antibody
PTGS1 Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG2b
Reactivity
Human
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1F12G7
验证数据展示
经过测试的应用
Positive IF detected in | HeLa cells |
For other applications, we recommend the unconjugated version of this antibody, 67346-1-Ig
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF) | IF : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-67346 targets PTGS1 in IF applications and shows reactivity with Human samples.
Tested Applications | IF/ICC |
Tested Reactivity | Human |
Immunogen | PTGS1 fusion protein Ag28280 种属同源性预测 |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Full Name | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
Synonyms | COX 1, COX1, COX3, Cyclooxygenase 1, PCOX1, PGG/HS, PGH synthase 1, PGHS 1, PGHS1, PHS 1, PHS1, Prostaglandin G/H synthase 1, Prostaglandin H2 synthase 1, PTGHS, PTGS1 |
Calculated Molecular Weight | 599 aa, 69 kDa |
Observed Molecular Weight | 60-72 kDa |
GenBank Accession Number | BC029840 |
Gene Symbol | PTGS1 |
Gene ID (NCBI) | 5742 |
RRID | AB_2919457 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P23219 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. |
背景介绍
PTGS1(Prostaglandin G/H synthase 1) belongs to the prostaglandin G/H synthase family and catalyzes the conversion of arachidonic acid to prostaglandin H2, which is subsequently metabolized to various biologically active prostaglandins. It is also named as COX1(Cyclooxygenase-1). There is no PTGS1 expression in fetal samples (prostate, seminal vesicles, or ejaculatory ducts), and only minimal expression in adult tissues (PMID: 10999846). PTGS1 has some isoforms with MW of 56-72 kD and PTGS1 can form homodimer.
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 PTGS1 antibody CL488-67346 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |