|Cell culture supernatants||101%||88%-109%|
IL28A, also known as IFNL2, is a cytokine distantly related to type I interferons and the IL-10 family. IL-28A, IL-28B and IL-29 are three closely related cytokines classiﬁed as type III IFNs, which share many of the biological effects of type I IFNs but may have fewer side effects due to a more selective receptor distribution. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). IL28A is believed to play a significant role in the antiviral immune defense in the intestinal epithelium.