CoraLite® Plus 488-conjugated DVL1 Monoclonal antibody
DVL1 Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG1
Reactivity
Human, rat, mouse
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1A2A5
验证数据展示
经过测试的应用
Positive IF detected in | MCF-7 cells |
For other applications, we recommend the unconjugated version of this antibody, 67672-1-Ig
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF) | IF : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-67672 targets DVL1 in IF applications and shows reactivity with Human, rat, mouse samples.
Tested Applications | IF/ICC |
Tested Reactivity | Human, rat, mouse |
Immunogen | DVL1 fusion protein Ag26083 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | dishevelled, dsh homolog 1 (Drosophila) |
Synonyms | Dishevelled 1, DSH homolog 1, DVL, DVL1 |
Calculated Molecular Weight | 75 kDa |
Observed Molecular Weight | 70-75 kDa |
GenBank Accession Number | BC050454 |
Gene Symbol | DVL1 |
Gene ID (NCBI) | 1855 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | O14640 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
DVL1 is one of three DVL homologous proteins (DVL1-3) widely expressed in embryonic development and in the adult central nervous system. Dishevelled proteins are a necessary component of the Wnt and planar cell polarity developmental signaling pathways. Overexpression of DVL1 has been linked to prostate and breast cancers through the Wnt signaling pathway. There are two isoforms of DVL1: 75 kDa and 73 kDa.
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 DVL1 antibody CL488-67672 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |