5-Methylcytosine (5-mC) antibody (rAb) (Clone RM231)
Host / Isotype
Rabbit / IgG
Reactivity
Human, Not Species Specific
Applications
DB, ICC, MeDIP
CloneNo.
RM231
Cat No : 91311 91311
Synonyms
验证数据展示
产品信息
Tested Applications |
DB, ICC, MeDIP
Validated Applications: DB: 0.5 - 2 ug/ml ICC: 0.5 - 2 ug/ml MeDIP: 0.2 - 2 ug/ml |
Tested Reactivity | Human, Not Species Specific |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | BSA-conjugated 5-methylcytosine. |
Full Name | 5-Methylcytosine (5-mC) antibody (rAb) (Clone RM231) |
Synonyms | 5-methylcytidine, methyl cytidine, 5 MeCyd, 5-Me, 5 MeC, MeDIP, methylated DNA immunoprecipitation, DNA methylation |
Molecular weight | |
GenBank accession number | N/A | Purification Method | Protein A Chromatography |
Buffer | PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide. Sodium azide is highly toxic. |
Storage | Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage. |
背景介绍
5-Methylcytosine (5-Methylcytidine) is a modified base that is found in the DNA of plants and vertebrates. DNA methylation is an epigenetic event in which DNA methyltransferases (DNMTs) catalyze the reaction of a methyl group to the fifth carbon of cytosine in a CpG dinucleotide. This modification helps to control gene expression and is also involved in genomic imprinting, while aberrant DNA methylation is often associated with disease.