• Featured Product
  • KD/KO Validated

MUTED/BLOC1S5 Polyclonal antibody

MUTED/BLOC1S5 Polyclonal Antibody for IF, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

IF, WB,ELISA

Conjugate

Unconjugated

Cat No : 24015-1-AP

Print datasheet

Synonyms

BL1S5, BLOC1S5, MU, MUTED, muted homolog (mouse), Protein Muted homolog



经过测试的应用

Positive WB detected inHEK-293T cells
Positive IF detected inHEK-293 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of 24015-1-AP is MUTED/BLOC1S5 Fusion Protein expressed in E. coli.

Tested Applications IF, WB,ELISA
Cited Applications WB
Tested Reactivity human
Cited Reactivityhuman, mouse
Immunogen MUTED/BLOC1S5 fusion protein Ag21226 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name muted homolog (mouse)
Synonyms BL1S5, BLOC1S5, MU, MUTED, muted homolog (mouse), Protein Muted homolog
Calculated Molecular Weight 187 aa, 22 kDa
Observed Molecular Weight 22-25 kDa
GenBank Accession NumberBC119644
Gene Symbol MUTED
Gene ID (NCBI) 63915
RRIDAB_2879402
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8TDH9
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

BLOC1S5 (biogenesis of lysosomal organelles complex 1 subunit 5) encodes a subunit of the BLOC1, a complex that is involved in transport of some but not all cargo to the lysosome and lysosome-related organelles. BLOC1S5 has a crucial role in STING-mediated cell death upon stimulation with low concentrations of CMA(PMID: 29033128).

实验方案

Product Specific Protocols
WB protocol for MUTED/BLOC1S5 antibody 24015-1-APDownload protocol
IF protocol for MUTED/BLOC1S5 antibody 24015-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Cell

The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.

Authors - Moritz M Gaidt
  • KO Validated
mouseWB

Cells

Dysbindin deficiency Alters Cardiac BLOC-1 Complex and Myozap Levels in Mice.

Authors - Ankush Borlepawar