PCDHA2 Polyclonal antibody

PCDHA2 Polyclonal Antibody for IP, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IP, WB,ELISA

Conjugate

Unconjugated

Cat No : 10127-2-AP

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Synonyms

PCDH alpha 2, PCDH ALPHA2, PCDHA2, protocadherin alpha 2



经过测试的应用

Positive WB detected inmouse brain tissue, Raji cells, human heart tissue, HeLa cells, human brain tissue, mouse cerebellum tissue, rat brain tissue, rat cerebellum tissue
Positive IP detected inHeLa cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10127-2-AP targets PCDHA2 in WB, IP,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IP, WB,ELISA
Tested Reactivity human, mouse, rat
Immunogen PCDHA2 fusion protein Ag0173 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name protocadherin alpha 2
Synonyms PCDH alpha 2, PCDH ALPHA2, PCDHA2, protocadherin alpha 2
Calculated Molecular Weight 102 kDa
Observed Molecular Weight 102 kDa, 80 kDa
GenBank Accession NumberBC003126
Gene Symbol PCDHA2
Gene ID (NCBI) 56146
RRIDAB_2158964
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9Y5H9
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). PCDHA2 (protocadherin alpha 2) is a single-pass type I membrane protein containing 6 cadherin domains. It may be involved in the establishment and maintenance of specific neuronal connections in the brain. Three isoforms produced by alternative splicing have been described (UniProt).

实验方案

Product Specific Protocols
WB protocol for PCDHA2 antibody 10127-2-APDownload protocol
IP protocol for PCDHA2 antibody 10127-2-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols