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  • KD/KO Validated

IFNAR1 Polyclonal antibody

IFNAR1 Polyclonal Antibody for FC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

FC, WB, ELISA and More (1)

Conjugate

Unconjugated

Cat No : 13083-1-AP

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Synonyms

AVP, CRF2 1, IFN alpha REC, IFN alpha/beta receptor 1, IFN R 1, IFNAR, IFNAR1, IFNBR, IFRC, Type I interferon receptor 1



经过测试的应用

Positive WB detected inJurkat cells, K-562 cell, mouse liver tissue
Positive FC detected inK-562 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Flow Cytometry (FC)FC : 0.20 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13083-1-AP targets IFNAR1 in WB, IF, FC, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications FC, WB, ELISA
Cited Applications IF, WB
Tested Reactivity human, mouse
Cited Reactivityhuman
Immunogen IFNAR1 fusion protein Ag3739 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name interferon (alpha, beta and omega) receptor 1
Synonyms AVP, CRF2 1, IFN alpha REC, IFN alpha/beta receptor 1, IFN R 1, IFNAR, IFNAR1, IFNBR, IFRC, Type I interferon receptor 1
Calculated Molecular Weight 557 aa, 64 kDa
Observed Molecular Weight 64 kDa
GenBank Accession NumberBC021825
Gene Symbol IFNAR1
Gene ID (NCBI) 3454
RRIDAB_2122626
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP17181
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects.

实验方案

Product Specific Protocols
WB protocol for IFNAR1 antibody 13083-1-APDownload protocol
FC protocol for IFNAR1 antibody 13083-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

EMBO Rep

Degradation of WTAP blocks antiviral responses by reducing the m 6 A levels of IRF3 and IFNAR1 mRNA

Authors - Yong Ge
humanWB

Elife

The oncoprotein BCL6 enables solid tumor cells to evade genotoxic stress.

Authors - Yanan Liu
  • KD Validated
humanWB,IF

Oncotarget

PMID: 26683360

Authors - Yujiao He
humanWB

Food Nutr Res

PMID: 27356910

Authors - Sheng Li
humanWB

Cell Rep

TDP-43 prevents endogenous RNAs from triggering a lethal RIG-I-dependent interferon response.

Authors - William Dunker
humanWB

J Nat Med

Baicalin promotes antiviral IFNs production and alleviates type I IFN-induced neutrophil inflammation

Authors - Li Li