CXCL13/BCA1 Polyclonal antibody

CXCL13/BCA1 Polyclonal Antibody for IHC, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, WB,ELISA and More (1)

Conjugate

Unconjugated

Cat No : 10927-1-AP

Print datasheet

Synonyms

ANGIE, ANGIE2, B cell attracting chemokine 1, B lymphocyte chemoattractant, BLC, BLR1L, C X C motif chemokine 13, CXC chemokine BLC, CXCL13, SCYB13, Small inducible cytokine B13



经过测试的应用

Positive WB detected inhuman placenta tissue, human plasma tissue, Jurkat cells
Positive IHC detected inhuman tonsillitis tissue, human renal cell carcinoma tissue, human breast cancer tissue, human lymphoma tissue, human liver tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10927-1-AP targets CXCL13/BCA1 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, WB,ELISA
Cited Applications IF, IHC, WB
Tested Reactivity human
Cited Reactivityhuman
Immunogen CXCL13/BCA1 fusion protein Ag1358 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name chemokine (C-X-C motif) ligand 13
Synonyms ANGIE, ANGIE2, B cell attracting chemokine 1, B lymphocyte chemoattractant, BLC, BLR1L, C X C motif chemokine 13, CXC chemokine BLC, CXCL13, SCYB13, Small inducible cytokine B13
Calculated Molecular Weight 13 kDa
Observed Molecular Weight 10 kDa
GenBank Accession NumberBC012589
Gene Symbol CXCL13
Gene ID (NCBI) 10563
RRIDAB_2086050
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO43927
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

BLR1 (Burkitt lymphoma receptor-1), also called CXCR5, is highly expressed on Burkitt lymphoma cells and B lymphocytes. It may therefore function in the homing of B lymphocytes to follicles. It was reported that the B cell chemokine CXCL13 is elevated in MS serum and cerebrospinal fluid. CXCL13 is also regarded as a proposed serum biomarker of synovitis in RA( Rheumatoid arthritis). CXCL13 consists of a 22-aa signal peptide and a 87-aa mature poly-peptide.

实验方案

Product Specific Protocols
WB protocol for CXCL13/BCA1 antibody 10927-1-APDownload protocol
IHC protocol for CXCL13/BCA1 antibody 10927-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

Sci Adv

Defined lifestyle and germline factors predispose Asian populations to gastric cancer.

Authors - Akihiro Suzuki
humanIF

Nat Commun

B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma.

Authors - Johannes Griss
humanIHC

Genomics

MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases.

Authors - Yuan Shi
humanWB

Aging (Albany NY)

Immune profiling reveals prognostic genes in high-grade serous ovarian cancer.

Authors - Yong Wu
humanIHC,IF

J Immunol

Villitis of unknown etiology is associated with a distinct pattern of chemokine up-regulation in the feto-maternal and placental compartments: implications for conjoint maternal allograft rejection and maternal anti-fetal graft-versus-host disease.

Authors - Kim Mi Jeong MJ
humanIHC,IF

Front Immunol

A Standardized Analysis of Tertiary Lymphoid Structures in Human Melanoma: Disease Progression- and Tumor Site-Associated Changes With Germinal Center Alteration.

Authors - Franziska Werner