COXIV Antibody 40 Publications

Rabbit Polyclonal| Catalog number: 11242-1-AP

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Species specificity:
human, mouse, rat, swine

Positive WB detected in:
MCF7 cells, A375 cells, A431 cells, A549 cells, HEK-293 cells, HeLa cells, HepG2 cells, human brain tissue, human lung tissue, human skeletal muscle tissue, human skin tissue, human spleen tissue, Jurkat cells, L02 cells, MCF-7 cells, mouse brain tissue, mouse heart tissue, mouse liver tissue, mouse skeletal muscle tissue, NIH/3T3 cells, rat brain tissue, rat liver tissue

Positive IP detected in:
mouse skeletal muscle tissue

Positive IHC detected in:
human prostate cancer tissue, human heart tissue, human pancreas tissue, human prostate cancer tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:400
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cytochrome c oxidase subunit IV isoform 1

Calculated molecular weight:
19.6 kDa

Observed molecular weight:
17-18 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
COX4I1

Synonyms
COX IV 1, COX4, COX4I1, COXIV, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit 4 isoform 1 mitochondrial
Background

COX4I1, also named as COX4 and COXIV-1, belongs to the cytochrome c oxidase IV family. It is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. COX4I1 is a marker for mitochondria. It has two isoforms (isoform 1 and 2). Isoform 1(COX4I1) is ubiquitously expressed and isoform 2 is highly expressed in lung tissues. COX4I1 is commonly used as a loading control. This antibody was generated against full length COX4I1 protein and cross reacts with COX4I2.


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