CFTR Monoclonal antibody
CFTR Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat, rabbit
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
2F4A8
验证数据展示
经过测试的应用
| Positive WB detected in | Calu-3 cells, HeLa cells, A431 cells, A375 cells, A549 cells, NCI-H1299 cells, HepG2 cells, MCF-7 cells, HT-29 cells, Caco-2 cells, MOLT-4 cells, rabbit brain tissue, rat brain tissue, mouse brain tissue |
Planning an IHC experiment? We recommend our IHCeasy CFTR Ready-To-Use IHC Kit. CFTR primary antibody included.
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
66928-1-Ig targets CFTR in WB, ELISA applications and shows reactivity with Human, mouse, rat, rabbit samples.
| Tested Applications | WB, ELISA |
| Tested Reactivity | Human, mouse, rat, rabbit |
| Immunogen | CFTR fusion protein Ag27810 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| Synonyms | ABC35, ABCC7, CF, CFTR, CFTR/MRP, dJ760C5.1, MRP7, TNR CFTR |
| Calculated Molecular Weight | 168 kDa |
| Observed Molecular Weight | 150 kDa |
| GenBank Accession Number | NM_000492 |
| Gene Symbol | CFTR |
| Gene ID (NCBI) | 1080 |
| RRID | AB_2882254 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P13569 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CFTR is a member of the ATP-binding cassette (ABC) family of membrane transport proteins, functioning as a chloride channel responsible for ion flow across epithelial surfaces of lung, sinuses, pancreas, intestine, and liver. Mutations of CFTR cause cystic fibrosis (CF), a disorder affecting the respiratory, digestive, reproductive systems and sweat glands.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for CFTR antibody 66928-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |