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CoraLite®594-conjugated Alpha Galactosidase A Monoclonal antibody

Alpha Galactosidase A Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

IF

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

2B2C5

Cat No : CL594-66121

Print datasheet

Synonyms

Alpha D galactosidase A, Alpha galactosidase A, GALA, galactosidase, alpha, GLA, Melibiase



经过测试的应用

Positive IF detected inHepG2 cells
For other applications, we recommend the unconjugated version of this antibody, 66121-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of CL594-66121 is Alpha Galactosidase A Fusion Protein expressed in E. coli.

Tested Applications IF
Tested Reactivity human
Immunogen Alpha Galactosidase A fusion protein Ag7505 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name galactosidase, alpha
Synonyms Alpha D galactosidase A, Alpha galactosidase A, GALA, galactosidase, alpha, GLA, Melibiase
Calculated Molecular Weight 49 kDa
Observed Molecular Weight 49 kDa
GenBank Accession NumberBC002689
Gene Symbol GLA
Gene ID (NCBI) 2717
RRIDAB_2883517
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission Maxima Wavelengths588 nm / 604 nm
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP06280
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

GLA, also named as Melibiase and Alpha-galactosidase A, belongs to the glycosyl hydrolase 27 family. It hydrolyzes terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids. Fabry disease is an X-linked lysosomal storage disorder resulting from the deficient activity of GLA. Enzyme replacement therapy (ERT) with GLA is currently the most effective therapeutic strategy for patients with Fabry disease, a lysosomal storage disease.

实验方案

Product Specific Protocols
IF protocol for CL594 Alpha Galactosidase A antibody CL594-66121Download protocol
Standard Protocols
Click here to view our Standard Protocols