AKT-phospho-S473 Antibody 2 Publications

Mouse Monoclonal| Catalog number: 66444-1-Ig |CloneNo.: 1C10B8

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规格

单价

50 μl

¥980

100 μl

¥1800

150 μl

¥2500


Species specificity:
human, mouse

Positive WB detected in:
Jurkat cells, HEK-293 cells

Positive IHC detected in:
human breast cancer tissue

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:100-1:400

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
v-akt murine thymoma viral oncogene homolog 1

Calculated molecular weight:

Observed molecular weight:
58-60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AKT1

Synonyms
AKT, AKT1, AKT1-phospho-S473, pakt, p-AKT, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha
Background

The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with phospho-modification at Ser473.


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