• Featured Product
  • KD/KO Validated

COX6A1 Polyclonal antibody

COX6A1 Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF, IHC, WB, ELISA

Conjugate

Unconjugated

Cat No : 11460-1-AP

Print datasheet

Synonyms

COX VIa L, COX6A, COX6A1, COX6AL



经过测试的应用

Positive WB detected inhuman brain tissue, NIH/3T3 cells
Positive IHC detected inhuman pancreas cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inMCF-7 cells, SH-SY5Y cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11460-1-AP targets COX6A1 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IF, IHC, WB, ELISA
Cited Applications IF, WB
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Immunogen COX6A1 fusion protein Ag2006 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name cytochrome c oxidase subunit VIa polypeptide 1
Synonyms COX VIa L, COX6A, COX6A1, COX6AL
Calculated Molecular Weight 85 aa, 9 kDa
Observed Molecular Weight 9.5 kDa
GenBank Accession NumberBC007723
Gene Symbol COX6A1
Gene ID (NCBI) 1337
RRIDAB_2085445
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP12074
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

COX6A1(Cytochrome c oxidase subunit 6A1, mitochondrial) is also named as COX6AL and belongs to the cytochrome c oxidase subunit 6A family.This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

实验方案

Product Specific Protocols
WB protocol for COX6A1 antibody 11460-1-APDownload protocol
IHC protocol for COX6A1 antibody 11460-1-APDownload protocol
IF protocol for COX6A1 antibody 11460-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
human,mouseWB,IF

Autophagy

PLK1 (polo like kinase 1)-dependent autophagy facilitates gefitinib-induced hepatotoxicity by degrading COX6A1 (cytochrome c oxidase subunit 6A1).

Authors - Peihua Luo
  • KD Validated
humanWB

Elife

Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome.

Authors - Yilin Kang
humanWB

Cell Death Dis

O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma.

Authors - Weicheng Wu
humanWB

Mol Cell Proteomics

HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV

Authors - Daniella H Hock
mouseWB

Hum Mol Genet

Pathological characterization of a novel mouse model expressing the PD-linked CHCHD2-T61I mutation.

Authors - Teresa R Kee
humanWB

Mol Cell Proteomics

HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV.

Authors - Daniella H Hock